Using Mouse Oocytes to Assess Human Gene Function During Meiosis IDiego Marin *1,2, Alexandra L. Nguyen *3, Richard T. Scott, Jr. 1,2, Karen Schindler 3
1IVI-RMA New Jersey, 2Jefferson College of Biomedical Sciences, Thomas Jefferson University, 3Department of Genetics, Rutgers, The State University of New Jersey
As the genetic variants associated with human disease begin to become uncovered, it is becoming increasingly important to develop systems with which to rapidly evaluate the biological significance of those identified variants. This protocol describes methods for evaluating human gene function during female meiosis I using mouse oocytes.
